Carefill 80 mg

• Supports firmer erections during sexual stimulation

• Helps maintain an erection during intercourse

• Improves the natural response to sexual arousal

• Offers a longer period of activity than many short-acting ED medicines

• Provides a convenient oral treatment

• Can improve confidence when erectile dysfunction is treated successfully

The response differs from person to person and depends on general health, the cause of erectile dysfunction and correct use of the medicine.

During sexual stimulation, the body releases nitric oxide. This increases a chemical called cGMP, which relaxes the smooth muscles and widens the blood vessels supplying the penis.

An enzyme called PDE5 normally breaks down cGMP. Tadalafil blocks this enzyme, allowing cGMP to remain active for longer. As a result, more blood can enter the penis and support a firm erection when the user is sexually aroused.

Carefill does not produce an erection without stimulation and does not act as a hormone or aphrodisiac.

Carefill 80 mg contains a high-strength dose of tadalafil and should be taken only when this specific strength has been prescribed by a qualified healthcare professional.

Swallow the prescribed amount with water, with or without food. Follow the timing stated on your prescription and do not take another dose because the first one appears to be working slowly. Sexual stimulation is required for the medicine to produce an erectile response.

Do not take more than the prescribed amount, repeat the dose within 24 hours or combine Carefill with another tadalafil or erectile dysfunction medicine. Do not split or crush the tablet unless your healthcare professional confirms that it is suitable to do so.

Kidney or liver problems and certain interacting medicines can affect how long tadalafil remains in the body. Seek urgent medical advice if you take more than the amount prescribed.

Common Side Effects

Carefill 80 mg can cause headache, facial flushing, indigestion, a blocked or runny nose, dizziness, nausea, back pain and muscle aches. These effects are usually temporary and improve as tadalafil leaves the body. Speak with a healthcare professional if any side effect becomes severe, continues for a long time or affects normal activities.

Serious Side Effects

Stop taking the medicine and obtain urgent medical help if you experience chest pain, fainting, severe breathing difficulty, swelling of the face or throat, sudden vision changes, sudden hearing loss or a seizure. An erection that is painful or lasts longer than four hours also requires immediate medical treatment to prevent lasting injury.

Carefill 80 mg is not suitable for everyone. It should be avoided by:

• People allergic to tadalafil

• People taking nitrate medicines

• People using nitrate-containing “poppers”

• People taking riociguat

• Men advised to avoid sexual activity

• People with severe low blood pressure

• People with uncontrolled high blood pressure

• People with certain serious heart conditions

• People with a recent heart attack or stroke without medical clearance

• People with previous tadalafil-related vision loss

• Women and anyone under 18 for ED treatment

People with liver disease, kidney disease, bleeding disorders, blood-cell conditions or anatomical changes to the penis require an individual medical assessment before treatment.

Tell your healthcare professional about every prescription medicine, non-prescription product and supplement you use.

Important interactions include:

• Nitrate medicines

• Riociguat

• Alpha-blockers

• Blood-pressure medicines

• Other PDE5 inhibitors

• Other tadalafil products

• Certain antifungal medicines

• Macrolide antibiotics

• HIV protease inhibitors

• Rifampicin

• Carbamazepine and phenytoin

• Excessive alcohol

• Grapefruit products

Nitrates and riociguat must not be combined with tadalafil because the combination can cause a dangerous fall in blood pressure. Other interacting medicines can increase tadalafil levels, reduce its effect or make side effects more likely.

Do not combine Carefill with another treatment for erectile dysfunction unless specifically instructed by a healthcare professional.

• Keep the tablets in their original packaging.

• Store them in a closed container at room temperature.

• Protect them from heat, moisture and direct sunlight.

• Do not store them in a damp bathroom.

• Keep them away from children and pets.

• Do not use damaged or discoloured tablets.

• Do not use the medicine after its expiry date.

• Ask a pharmacist how to dispose of unused tablets safely.