Carefill 20 mg

• Helps improve erections in men with ED

• Supports better penile blood flow

• Helps maintain an erection during sexual activity

• May remain effective for up to 36 hours

• Allows greater flexibility in the timing of intimacy

• Can be taken with or without food

• Comes as a convenient oral tablet

The medicine manages erectile dysfunction while it is active. It does not permanently cure ED or remove an underlying medical or psychological cause.

During sexual stimulation, the body releases nitric oxide in the penis. This increases a natural chemical called cyclic guanosine monophosphate, or cGMP, which relaxes smooth muscles and allows more blood to enter the penile tissues.

An enzyme called PDE5 normally breaks down cGMP. Tadalafil blocks this enzyme, allowing cGMP to remain active for longer. The resulting improvement in blood flow can help a man achieve and maintain an erection when sexually aroused.

Carefill 20 mg supports the physical erectile response. It does not treat low sexual desire or work without sexual stimulation.

For most adult men using tadalafil as needed, treatment usually begins with 10 mg taken before anticipated sexual activity. A healthcare professional may increase the dose to 20 mg or reduce it to 5 mg based on effectiveness, tolerability and the person’s health.

Carefill 20 mg contains the maximum commonly recommended as-needed tadalafil dose. Take it only when this strength has been prescribed. Swallow the tablet with water at least 30 minutes before sexual activity. It may be taken with or without food.

Do not take more than one dose within 24 hours or take an additional tablet when the first dose does not work immediately. Carefill 20 mg is not intended to be used as a routine daily dose unless a qualified healthcare professional provides specific instructions.

People with kidney or liver problems and those using certain interacting medicines may need a lower dose or a longer interval between doses. Because Carefill 20 mg is generally taken when required, there is no missed dose to replace.

Common Side Effects: Headache, indigestion, facial warmth or flushing, a stuffy nose, back pain, muscle aches and pain in the arms or legs may occur. Back pain and muscle discomfort can appear several hours after taking tadalafil and usually settle without treatment. Speak with a healthcare professional if a side effect is severe, persistent or difficult to manage.

Serious Side Effects: Obtain urgent medical help for chest pain, fainting, severe dizziness, sudden vision loss, sudden hearing loss, facial or throat swelling, breathing difficulty or an erection that is painful or lasts longer than four hours. Do not take another dose until the symptoms have been medically assessed.

Carefill 20 mg is unsuitable for some people and should not be taken without medical approval by:

• People allergic to tadalafil

• People using nitrate medicines

• People taking riociguat

• Men advised to avoid sexual activity

• People with severe heart disease

• People with very low blood pressure

• People with severe liver disease

• People with serious kidney impairment

• Children and adolescents

• People using another PDE5 inhibitor

A medical assessment is particularly important after a recent heart attack or stroke or when there is uncontrolled high blood pressure, an irregular heartbeat or a previous serious eye condition.

Tell your healthcare provider about every medicine, supplement and recreational substance you use. Important interactions include:

• Nitrate medicines

• Riociguat

• Alpha-blockers

• Blood pressure medicines

• Other PDE5 inhibitors

• Other erectile dysfunction treatments

• Ketoconazole or itraconazole

• Ritonavir and similar HIV medicines

• Certain macrolide antibiotics

• Excessive alcohol

Combining tadalafil with nitrates or riociguat can cause a dangerous fall in blood pressure. Strong CYP3A4-inhibiting medicines can increase tadalafil levels and may make the 20 mg strength unsuitable.

Do not combine Carefill 20 mg with sildenafil, vardenafil, avanafil, another tadalafil product or any other ED treatment unless specifically instructed by a healthcare professional.

• Keep the tablets in their original packaging.

• Store them at room temperature.

• Protect them from heat, moisture and direct sunlight.

• Do not store them in a bathroom or near a sink.

• Keep them away from children and pets.

• Do not use damaged or discoloured tablets.

• Do not take the medicine after its expiry date.

• Follow any additional instructions printed on the pack.