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Avanafil is a prescription medicine used to treat erectile dysfunction in adult men. It supports an erection during sexual stimulation and is commonly available in 50 mg, 100 mg and 200 mg tablets. Browse available avanafil tablets at KwickPharmacy. Compare the strength, manufacturer, pack size and prescription status before ordering.
Avanafil is a phosphodiesterase type 5 (PDE5) inhibitor used to treat erectile dysfunction (ED) in adult men. Stendra is the brand name used in the United States, while Spedra is marketed in the United Kingdom and some European countries. Generic avanafil may also be available in certain markets, although availability, strengths, and approved formulations can vary by country.
Avanafil is designed to help improve blood flow to the penis during sexual stimulation. Depending on the prescribed strength and product instructions, it may be taken approximately 15 minutes before sexual activity. Avanafil does not automatically produce an erection, increase testosterone levels, or directly increase sexual desire. Sexual stimulation is required for an erection to occur, and the medicine should be used according to the prescribed instructions.
Avanafil is used to treat erectile dysfunction (ED), also known as impotence, in adult men. Erectile dysfunction is a condition in which a person has difficulty achieving or maintaining an erection that is firm enough for satisfactory sexual activity. Avanafil belongs to the PDE5 inhibitor class and works by improving blood flow to the penis during sexual stimulation, helping support the body's normal erectile response.
ED can be associated with underlying conditions such as diabetes, cardiovascular disease, high blood pressure, or hormonal and neurological disorders. Certain medicines, as well as psychological factors such as stress and anxiety, can also contribute to erectile difficulties. Avanafil helps manage the erectile symptoms but does not cure the underlying cause of ED or protect against sexually transmitted infections (STIs). Persistent or newly developed ED should be discussed with a healthcare professional because it may sometimes indicate an underlying health condition.
Avanafil can help eligible adult men with erectile dysfunction (ED) achieve and maintain an erection that is firm enough for sexual activity when sexual stimulation is present. One practical benefit is its relatively rapid onset of action, with some prescribed strengths designed to be taken shortly before sexual activity. Avanafil is also used as needed, rather than necessarily requiring daily treatment. Taking avanafil with a high-fat meal may delay its absorption and reduce how quickly its effects begin.
The most suitable PDE5 inhibitor depends on factors such as response to treatment, preferred timing, medical conditions, other medicines, and potential drug interactions. A faster onset does not mean avanafil is automatically stronger or more effective than other ED medicines. Use it only as directed by a healthcare professional and do not increase the dose to try to achieve a stronger effect.
Avanafil works by supporting the body's natural erection process during sexual stimulation. Sexual stimulation causes the release of nitric oxide in erectile tissue, which increases levels of cyclic guanosine monophosphate (cGMP). cGMP helps relax the smooth muscle in the penis, allowing increased blood flow into the erectile tissue and supporting an erection.
Avanafil is a PDE5 inhibitor, meaning it blocks the phosphodiesterase type 5 (PDE5) enzyme that normally breaks down cGMP. By slowing cGMP breakdown, avanafil helps maintain the signalling needed for increased penile blood flow when sexual stimulation occurs. Avanafil does not cause a continuous or automatic erection; sexual stimulation is still required for its effects to occur.
The usual adult starting dose is avanafil 100 mg taken as needed, as early as 15 minutes before sexual activity. A prescriber may reduce it to 50 mg, usually taken about 30 minutes beforehand, or increase it to 200 mg.
Take no more than one dose in 24 hours. Avanafil may be taken with or without food. Do not repeat an unsuccessful dose or combine it with another ED medicine unless specifically directed.
Dosage may change with interacting medicines. Viagra, Cialis and avanafil milligrams are not equivalent.
Possible avanafil side effects include headache, facial flushing or a feeling of warmth, a stuffy or runny nose, sore throat or cold-like symptoms, back pain, dizziness, and indigestion or stomach discomfort. These effects are often mild and temporary, but persistent or bothersome symptoms should be discussed with a healthcare professional.
Seek urgent medical attention if you experience chest pain, fainting, signs of a severe allergic reaction, sudden vision loss, or sudden hearing loss. An erection lasting more than four hours (priapism) is also a medical emergency because prolonged erection can cause permanent damage to penile tissue. If chest pain occurs after taking avanafil, tell emergency medical professionals when you last took the medicine. Do not take nitrate medicines such as nitroglycerin to self-treat chest pain after using avanafil, as the combination can cause a dangerous drop in blood pressure.
Avanafil should never be combined with nitrate medicines, recreational “poppers” containing nitrates or nitrites, or guanylate cyclase stimulators such as riociguat. These combinations can cause a sudden and potentially dangerous drop in blood pressure, which may lead to dizziness, fainting, or serious cardiovascular complications. Tell your healthcare professional about all medicines and recreational substances you use before taking avanafil.
Strong CYP3A4 inhibitors, including ketoconazole, itraconazole, clarithromycin, and ritonavir, can substantially increase avanafil levels and should not be combined with avanafil. Moderate CYP3A4 inhibitors may also increase exposure and can require a lower avanafil dose or other adjustments. Alpha-blockers, antihypertensive medicines, and substantial alcohol consumption may further increase the risk of dizziness, fainting, or low blood pressure. Do not change or combine medicines without discussing potential interactions with your healthcare professional.
Avanafil should not be taken by people with a known allergy to avanafil or any of its ingredients. It must also not be used with nitrate medicines, recreational “poppers,” or guanylate cyclase stimulators such as riociguat, because these combinations can cause a dangerous drop in blood pressure. Avanafil may also be unsuitable for people with certain serious cardiovascular conditions, including a recent heart attack or stroke, unstable or severe heart disease, or very low or uncontrolled blood pressure. Tell your healthcare professional about any history of cardiovascular disease before using avanafil.
People with severe kidney impairment or severe liver impairment may require avoidance or specialist assessment because the medicine may not be appropriate or may have altered exposure. Avanafil should also be avoided in people with a previous history of non-arteritic anterior ischemic optic neuropathy (NAION) or sudden vision loss attributed to NAION. A healthcare professional should review your medical history and current medicines before prescribing avanafil to determine whether it is safe and appropriate.
Store avanafil tablets in their original packaging at the room temperature specified on the product label. Protect the medicine from excessive heat, moisture, and direct light, and keep it out of reach of children. Do not use tablets after their expiry date or if they have been damaged or stored improperly. Ask a pharmacist or follow local medication-disposal guidance for the safe disposal of expired or unused avanafil.
There is no universal answer. Avanafil and Viagra (sildenafil) have different strengths and are not directly comparable by milligrams. Avanafil may work sooner for some people, but effectiveness and tolerability vary.